Recently, one of the hottest topics in the world of fitness is SARMs, i.e. selective androgen receptor modulators. In the process to find the best legal steroids at the Legal Steroid Guide you can actually come up with the results.
A special feature?
Their anabolic effect is much more expressed than in the case of steroids (SAA). It can be several or even several dozen times greater than the undesirable androgenic effect. For comparison, with steroids these proportions are 1: 1 vs. even 90: 1 at SARMs. However, SARMs are not supplements.
All the other SARMs must first leave the mouse labs. Until human clinical trials are conducted, any experimentation with them should be excluded.
What are SARMs?
SARMs are in the group of compounds from the area of experimental bio hacking, i.e. its most risky version. We would describe them as a use-for-your-own measure.
On the internet, they are advertised as legal steroids, which certainly attract the attention of young growth adepts who are unfamiliar with marketing bullshit. Despite the incomparably higher proportions of anabolic to androgenic effects, SARMs can cause all side effects seen with anabolic steroids.
However, they occur less frequently at higher doses and only occur during prolonged use. Headaches, insomnia, mood disorders and increased liver enzymes (ALT, AST) are common. However, liver damage is rare, and prostate hyperplasia, gynecomastia or e.g. breast cancer in men are extremely rare.
SARMs can contribute to the reduction of natural testosterone production. At the same time, they reduce the concentration of SHGB (testosterone binding) protein, so a reduction in endogenous testosterone levels is often not felt. After all, you need to be very careful.
Why do SARMs work differently than steroids?
Steroids interact with many tissues at the same time, leading to a litany of side effects such as prostate hyperplasia. The phenomenon of SARMs is that they are selective and affect only skeletal muscles.
They do not have a steroid structure, so they are not converted to active metabolites – aromatase action and conversion to estradiol. They are also not affected by 5-alpha-reductase and converted to dihydrotestosterone.
Moreover, at the time of writing this article, SARMs are completely legal and available in oral form. This eliminates the need for frequent injections.
There are currently over a dozen human clinical trials in the world using SARMs. Estuarine and lingandrol are the best tested. Here’s what they characterize.
MK-2866 side effects
To date, no significant side effects have been found in human studies. Looking through bodybuilding forums, however, you can come across anecdotal reports of users taking high doses of estuarine for a period of 8-12 weeks who report short-term testosterone suppression. At the end of the cycle, testosterone returned to their regular levels.
What doses of ostarine MK-2866 are effective?
Due to the fact that SARMs have been in circulation for a short time, there are no official dosage recommendations. If I were interested in experimenting with ostarine, I would consider doses based on clinical trials.
At present, it would be 15-20mg per day for a period of 4 weeks. Then 4 weeks break for the balance, after which I would again enter the 4 week cycle of ostarine Plus regular strength sessions and HIIT workouts.